Intracytoplasmic morphologically selected sperm injection (IMSI)
Intracytoplasmic morphologically selected sperm injection (IMSI), employed in the context of in vitro fertilization (IVF), allows doctors to differentiate the structural and morphological characteristics of sperm and exclude any potential abnormalities.
Procedure:
It involves the use of a high magnification DIC (differential interface contrast) microscopy to aid in the precise evaluation and selection of sperm cell prior to injection into the egg.
IMSI proves especially beneficial in cases of severe male infertility. Moreover, it empowers physicians to distinguish between healthy and aberrant sperm, further enhancing the chances of successful fertilization.
Who is IMSI-IVF recommended for?
IMSI treatment is advised for men who exhibit the following conditions:
- A high proportion of abnormally shaped sperm.
- High DNA fragmentation index.
- A history of unsatisfactory outcomes from prior ICSI-IVF cycles.
- Sperm retrieved through surgical procedures.
IMSI treatment is recommended for women in the following situations:
- Previous failed IVF cycles.
- A history of recurrent miscarriages.
- Failure of egg implantation despite having normal-quality eggs.
- The presence of a limited number of eggs.
Who is IMSI-IVF recommended for?
IMSI demonstrated statistically improved pregnancy rate, increased incidence of euploid embryos and significant reduction in miscarriage rates. This advanced technique has notably enhanced outcomes for men facing severe fertility challenges and has proven advantageous for couples who have previously experienced unsuccessful IVF-ICSI cycles. Additionally, IMSI has also provided benefits to couples grappling with unexplained infertility.
